7D99

human potassium-chloride co-transporter KCC4

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	potassium-chloride co-transporter KCC4	polymer	1113	123069.5	2	UniProt (Q9Y666) Pfam (PF00324) Pfam (PF03522)	Homo sapiens (Human)	Electroneutral potassium-chloride cotransporter 4,K-Cl cotransporter 4
2	C, D, E, F (C, D, E, F)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	4	In PDB GlyTouCan (G42666HT)
3	G, J (A, B)	POTASSIUM ION	non-polymer		39.1	2	Chemie (K)
4	H, I, K, L (A, B)	CHLORIDE ION	non-polymer		35.5	4	Chemie (CL)

Sequence modifications

A, B: 1 - 1083 (UniProt: Q9Y666)

PDB	External Database	Details
Met -21	-	initiating methionine
Asp -20	-	expression tag
Tyr -19	-	expression tag
Lys -18	-	expression tag
Asp -17	-	expression tag
Asp -16	-	expression tag
Asp -15	-	expression tag
Asp -14	-	expression tag
Lys -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
Glu -6	-	expression tag
Asn -5	-	expression tag
Leu -4	-	expression tag
Tyr -3	-	expression tag
Phe -2	-	expression tag
Gln -1	-	expression tag
Gly 0	-	expression tag
Trp 1084	-	expression tag
Ser 1085	-	expression tag
His 1086	-	expression tag
Pro 1087	-	expression tag
Gln 1088	-	expression tag
Phe 1089	-	expression tag
Glu 1090	-	expression tag
Lys 1091	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	246139.0
Branched	Number of molecules	4
	Total formula weight	1697.6
Non-Polymers*	Number of molecules	6
	Total formula weight	220.0
All*	Total formula weight	248056.6

*Water molecules are not included.