7D93

Crystal Structure of the Na+,K+-ATPase in the E2P state with bound Mg2+ and anthroylouabain (P2(1)2(1)2(1) symmetry)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	Sodium/potassium-transporting ATPase subunit alpha-1	polymer	1016	112403.9	2	UniProt (P05024) Pfam (PF00690) Pfam (PF00122) Pfam (PF13246) Pfam (PF00702) Pfam (PF00689) In PDB	Sus scrofa (Pig)	Na(+)/K(+) ATPase alpha-1 subunit,Sodium pump subunit alpha-1
2	B, D	Sodium/potassium-transporting ATPase subunit beta-1	polymer	303	35204.4	2	UniProt (P05027) Pfam (PF00287) In PDB	Sus scrofa (Pig)	Sodium/potassium-dependent ATPase subunit beta-1
3	E, G	FXYD domain-containing ion transport regulator	polymer	65	7094.1	2	UniProt (Q58K79) Pfam (PF02038) In PDB	Sus scrofa (Pig)	Na+/K+ ATPase gamma subunit transcript variant a
4	F, H, I, J	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	4	In PDB GlyTouCan (G42666HT)
5	A, C	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG)
6	A, C	SODIUM ION	non-polymer		23.0	2	Chemie (NA)
7	D, E, G, A	CHOLESTEROL	non-polymer		386.7	5	Chemie (CLR)
8	C, D, A	1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE	non-polymer		787.1	11	Chemie (PCW)
9	C, A	[(2~{R},3~{R},4~{R},5~{S},6~{S})-2-[[(1~{R},3~{S},5~{S},8~{R},9~{S},10~{R},11~{R},13~{R},14~{S},17~{R})-10-(hydroxymethyl)-13-methyl-1,5,11,14-tetrakis(oxidanyl)-17-(5-oxidanylidene-2~{H}-furan-3-yl)-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1~{H}-cyclopenta[a]phenanthren-3-yl]oxy]-6-methyl-3,5-bis(oxidanyl)oxan-4-yl] anthracene-9-carboxylate	non-polymer		788.9	2	Chemie (H0C)
10	D, B	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
11		water	water		18.0	12	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	309404.9
Branched	Number of molecules	4
	Total formula weight	1697.6
Non-Polymers*	Number of molecules	26
	Total formula weight	12755.0
All*	Total formula weight	323857.5

*Water molecules are not included.