7D85
Crystal structure of anti-ErbB3 Fab ISU104 in complex with human ErbB3 extracellular domain 3
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D | Receptor tyrosine-protein kinase erbB-3 | polymer | 194 | 21490.6 | 2 | UniProt (P21860) Pfam (PF01030) In PDB | Homo sapiens (Human) | Proto-oncogene-like protein c-ErbB-3,Tyrosine kinase-type cell surface receptor HER3 |
| 2 | B, E | Anti-ErbB3 Fab heavy chain | polymer | 228 | 24252.0 | 2 | Homo sapiens | ||
| 3 | C, F | Anti-ErbB3 Fab light chain | polymer | 216 | 22663.9 | 2 | Homo sapiens | ||
| 4 | A, D | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 7 | Chemie (NAG) | |||
| 5 | water | water | 18.0 | 39 | Chemie (HOH) |
Sequence modifications
A, D: 309 - 500 (UniProt: P21860)
| PDB | External Database | Details |
|---|---|---|
| Gly 307 | - | expression tag |
| Ile 308 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 136813.0 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1548.5 | |
| All* | Total formula weight | 138361.5 |
