7D7E

Structure of PKD1L3-CTD/PKD2L1 in apo state

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	B, C, D	Polycystic kidney disease 2-like 1 protein	polymer	604	69234.7	3	UniProt (A2A259) Pfam (PF20519) Pfam (PF00520) Pfam (PF08016) In PDB	Mus musculus (Mouse)	Polycystin-2 homolog
2	A	Polycystic kidney disease protein 1-like 3	polymer	551	62541.9	1	UniProt (Q2EG98) Pfam (PF20519) Pfam (PF00520) Pfam (PF08016) In PDB	Mus musculus (Mouse)	PC1-like 3 protein,Polycystin-1L3
3	B, C, D, A	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	10	Chemie (NAG)
4	B, C, D	CALCIUM ION	non-polymer		40.1	3	Chemie (CA)

Sequence modifications

B, C, D: 64 - 629 (UniProt: A2A259)

PDB	External Database	Details
Met 26	-	initiating methionine
Gly 27	-	expression tag
Ser 28	-	expression tag
Ala 29	-	expression tag
Gly 30	-	expression tag
Trp 31	-	expression tag
Ser 32	-	expression tag
His 33	-	expression tag
Pro 34	-	expression tag
Gln 35	-	expression tag
Phe 36	-	expression tag
Glu 37	-	expression tag
Lys 38	-	expression tag
Gly 39	-	expression tag
Gly 40	-	expression tag
Gly 41	-	expression tag
Ser 42	-	expression tag
Gly 43	-	expression tag
Gly 44	-	expression tag
Gly 45	-	expression tag
Ser 46	-	expression tag
Gly 47	-	expression tag
Gly 48	-	expression tag
Ser 49	-	expression tag
Ala 50	-	expression tag
Trp 51	-	expression tag
Ser 52	-	expression tag
His 53	-	expression tag
Pro 54	-	expression tag
Gln 55	-	expression tag
Phe 56	-	expression tag
Glu 57	-	expression tag
Lys 58	-	expression tag
Gly 59	-	expression tag
Ser 60	-	expression tag
Ala 61	-	expression tag
Ala 62	-	expression tag
Ala 63	-	expression tag

A: 1632 - 2150 (UniProt: Q2EG98)

PDB	External Database	Details
Met 1600	-	initiating methionine
Gly 1601	-	expression tag
Ser 1602	-	expression tag
Ala 1603	-	expression tag
Gly 1604	-	expression tag
Asp 1605	-	expression tag
Tyr 1606	-	expression tag
Lys 1607	-	expression tag
Asp 1608	-	expression tag
His 1609	-	expression tag
Asp 1610	-	expression tag
Gly 1611	-	expression tag
Asp 1612	-	expression tag
Tyr 1613	-	expression tag
Lys 1614	-	expression tag
Asp 1615	-	expression tag
His 1616	-	expression tag
Asp 1617	-	expression tag
Ile 1618	-	expression tag
Asp 1619	-	expression tag
Tyr 1620	-	expression tag
Lys 1621	-	expression tag
Asp 1622	-	expression tag
Asp 1623	-	expression tag
Asp 1624	-	expression tag
Asp 1625	-	expression tag
Lys 1626	-	expression tag
Gly 1627	-	expression tag
Ser 1628	-	expression tag
Ala 1629	-	expression tag
Ala 1630	-	expression tag
Ala 1631	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	270246.1
Non-Polymers*	Number of molecules	13
	Total formula weight	2332.3
All*	Total formula weight	272578.4

*Water molecules are not included.