7D6N

Crystal structure of tick-borne encephalitis virus RNA-dependent RNA polymerase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, E, D, C...	Tick-borne encephalitis virus RNA-dependent RNA polymerase	polymer	638	73561.7	10	UniProt (K4P8A2) Pfam (PF00972) Pfam (PF20483) In PDB	Tick-borne encephalitis virus	Envelope protein E,Flavivirin protease NS2B regulatory subunit,Flavivirin protease NS3 catalytic subunit,Genome polyprotein,Matrix protein,Non-structural protein 1,Non-structural protein 2A,Non-structural protein 2B,Non-structural protein 3,Non-structural protein 4A,Non-structural protein 4B,Peptide 2k,Peptide pr,Protein prM,RNA-directed RNA polymerase NS5,Serine protease NS3,Serine protease subunit NS2B,Small envelope protein M
2	F, G, J, I, A...	ZINC ION	non-polymer		65.4	20	Chemie (ZN)
3	F, G, J, I, A...	MAGNESIUM ION	non-polymer		24.3	10	Chemie (MG)

Sequence modifications

A, B, E, D, C, F, G, J, I, H: 265 - 891 (UniProt: K4P8A2)

PDB	External Database	Details
Met 264	-	initiating methionine
Gly 892	-	expression tag
Ser 893	-	expression tag
Ser 894	-	expression tag
Ser 895	-	expression tag
His 896	-	expression tag
His 897	-	expression tag
His 898	-	expression tag
His 899	-	expression tag
His 900	-	expression tag
His 901	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	10
	Total formula weight	735617.0
Non-Polymers*	Number of molecules	30
	Total formula weight	1551.2
All*	Total formula weight	737168.2

*Water molecules are not included.