7D5Q

Structure of NorC transporter (K398A mutant) in an outward-open conformation in complex with a single-chain Indian camelid antibody

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Drug transporter, putative	polymer	479	50855.2	2	UniProt (A0A0H2WZS4) Pfam (PF07690)	Staphylococcus aureus subsp. aureus COL
2	C, D (C, D)	ICab	polymer	131	14257.7	2		Camelus dromedarius
3	E, F (C, D)	ZINC ION	non-polymer		65.4	2	Chemie (ZN)

Sequence modifications

A, B: 1 - 462 (UniProt: A0A0H2WZS4)

PDB	External Database	Details
Ala 398	Lys 398	engineered mutation
Gly 463	-	expression tag
Thr 464	-	expression tag
Leu 465	-	expression tag
Val 466	-	expression tag
Pro 467	-	expression tag
Arg 468	-	expression tag
Gly 469	-	expression tag
Ser 470	-	expression tag
Gly 471	-	expression tag
His 472	-	expression tag
His 473	-	expression tag
His 474	-	expression tag
His 475	-	expression tag
His 476	-	expression tag
His 477	-	expression tag
His 478	-	expression tag
His 479	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	130225.7
Non-Polymers*	Number of molecules	2
	Total formula weight	130.8
All*	Total formula weight	130356.5

*Water molecules are not included.