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7D4Q

Structure of human TRPC5 in complex with HC-070

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Short transient receptor potential channel 5polymer76488848.64UniProt (Q9UL62)
Pfam (PF12796)
Pfam (PF00023)
Pfam (PF08344)
Pfam (PF00520)
Homo sapiens (Human)TrpC5,Transient receptor protein 5,hTRP5
2E, K, Q, W
(A, B, C, D)
PHOSPHATIDYLETHANOLAMINEnon-polymer734.04Chemie (PTY)
3F, L, R, X
(A, B, C, D)
(2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphatenon-polymer760.14Chemie (POV)
4G, M, S, Y
(A, B, C, D)
CHOLESTEROL HEMISUCCINATEnon-polymer486.74Chemie (Y01)
5H, N, T, Z
(A, B, C, D)
ZINC IONnon-polymer65.44Chemie (ZN)
6AA, I, O, U
(D, A, B, C)
CALCIUM IONnon-polymer40.14Chemie (CA)
7BA, J, P, V
(D, A, B, C)
8-(3-chloranylphenoxy)-7-[(4-chlorophenyl)methyl]-3-methyl-1-(3-oxidanylpropyl)purine-2,6-dionenon-polymer475.34Chemie (GWR)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight355394.3
Non-Polymers*Number of molecules24
Total formula weight10246.6
All*Total formula weight365640.9
*Water molecules are not included.

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PDB entries from 2026-01-14

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