7D30
Structure of sybody MR17-SR31 fusion in complex with the SARS-CoV-2 S Receptor Binding domain (RBD)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | sybody fusion of MR17-SR31 with a GS linker | polymer | 298 | 31220.1 | 1 | synthetic construct | ||
| 2 | B (B) | Spike protein S1 | polymer | 213 | 23747.6 | 1 | UniProt (P0DTC2) Pfam (PF09408) | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) | S glycoprotein,E2,Peplomer protein |
| 3 | C (C) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)][alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1041.0 | 1 | In PDB GlyTouCan (G17601US) | |||
| 4 | D, HA, IA, K, NA (A, B) | GLYCEROL | non-polymer | 92.1 | 5 | Chemie (GOL) | |||
| 5 | CA, E, EA, F, FA... (B, A) | ACETATE ION | non-polymer | 59.0 | 14 | Chemie (ACT) | |||
| 6 | DA, H (B, A) | PENTAETHYLENE GLYCOL | non-polymer | 238.3 | 2 | Chemie (1PE) | |||
| 7 | L, LA, M, MA, N (A, B) | 1,3-BUTANEDIOL | non-polymer | 90.1 | 5 | Chemie (BU2) | |||
| 8 | AA, BA, PA, Q, QA... (A, B) | CADMIUM ION | non-polymer | 112.4 | 17 | Chemie (CD) | |||
| 9 | UA, VA (A, B) | water | water | 18.0 | 219 | Chemie (HOH) |
Sequence modifications
B: 330 - 531 (UniProt: P0DTC2)
| PDB | External Database | Details |
|---|---|---|
| Ala 327 | - | expression tag |
| Gly 328 | - | expression tag |
| Ser 329 | - | expression tag |
| Gly 532 | - | expression tag |
| Thr 533 | - | expression tag |
| Leu 534 | - | expression tag |
| Glu 535 | - | expression tag |
| Val 536 | - | expression tag |
| Leu 537 | - | expression tag |
| Phe 538 | - | expression tag |
| Gln 539 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 54967.8 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 1041.0 | |
| Non-Polymers* | Number of molecules | 43 |
| Total formula weight | 4125.2 | |
| All* | Total formula weight | 60134.0 |
