7CZY

S protein of SARS-CoV-2 in complex bound with P5A-2F11_2B

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	Spike glycoprotein	polymer	1283	142502.6	3	UniProt (P0DTC2) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601)	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)	S glycoprotein,E2,Peplomer protein
2	D, F (H, J)	Immunoglobulin heavy variable 1-8,Immunoglobulin heavy variable 1-8,chain H of P5A-2F11_2B,Epididymis luminal protein 214,Epididymis luminal protein 214	polymer	452	49448.7	2	UniProt (P0DP01) UniProt (V9HW68) Pfam (PF07686) Pfam (PF07654)	Homo sapiens (Human)
3	E, G (K, N)	IG c168_light_IGKV4-1_IGKJ4,Immunoglobulin kappa constant	polymer	220	24158.8	2	UniProt (A0A5C2G1U0) UniProt (P01834) Pfam (PF07654) Pfam (PF07686)	Homo sapiens (Human)	IGL c2410_light_IGKV4-1_IGKJ4,IGL c2520_light_IGKV4-1_IGKJ4,Ig kappa chain C region,Ig kappa chain C region AG,Ig kappa chain C region CUM,Ig kappa chain C region EU,Ig kappa chain C region OU,Ig kappa chain C region ROY,Ig kappa chain C region TI
4	AA, BA, H, I, J... (a, b, D, E, F...)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	21	In PDB GlyTouCan (G42666HT)
5	CA, DA (c, d)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		627.6	2	In PDB GlyTouCan (G47362BJ)
6	AB, BB, CB, DB, EA... (C, A, B)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	28	Chemie (NAG)

Sequence modifications

A, B, C: 1 - 1273 (UniProt: P0DTC2)

PDB	External Database	Details
Pro 986	Lys 986	conflict
Pro 987	Val 987	conflict
Leu 1274	-	expression tag
Glu 1275	-	expression tag
Asp 1276	-	expression tag
Tyr 1277	-	expression tag
Lys 1278	-	expression tag
Asp 1279	-	expression tag
Asp 1280	-	expression tag
Asp 1281	-	expression tag
Asp 1282	-	expression tag
Lys 1283	-	expression tag

H, J: 1 - 98 (UniProt: P0DP01)
H, J: 99 - 108 (PDB: 7CZY)
H, J: 109 - 452 (UniProt: V9HW68)
K, N: 1 - 113 (UniProt: A0A5C2G1U0)
K, N: 114 - 220 (UniProt: P01834)

Contents of the asymmetric unit

Polymers	Number of chains	7
	Total formula weight	574722.7
Branched	Number of molecules	23
	Total formula weight	10167.6
Non-Polymers*	Number of molecules	28
	Total formula weight	6193.8
All*	Total formula weight	591084.2

*Water molecules are not included.