7CYP
Complex of SARS-CoV-2 spike trimer with its neutralizing antibody HB27
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | SARS-CoV-2 Spike glycoprotein | polymer | 1208 | 133865.4 | 3 | UniProt (P0DTC2) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601) | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) | S glycoprotein,E2,Peplomer protein |
| 2 | D, F, H (D, F, H) | Light chain of HB27 | polymer | 110 | 11921.3 | 3 | Homo sapiens | ||
| 3 | E, G, I (E, G, I) | Heavy chain of HB27 | polymer | 119 | 12917.4 | 3 | Homo sapiens | ||
| 4 | J, K, L, M, N... (J, K, L, M, N...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 15 | In PDB GlyTouCan (G42666HT) | |||
| 5 | AA, AB, BA, CA, DA... (A, C, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 29 | Chemie (NAG) |
Sequence modifications
A, B, C: 1 - 1208 (UniProt: P0DTC2)
| PDB | External Database | Details |
|---|---|---|
| Gly 682 | Arg 682 | engineered mutation |
| Ser 683 | Arg 683 | engineered mutation |
| Ser 685 | Arg 685 | engineered mutation |
| Met 835 | Lys 835 | engineered mutation |
| Met 844 | Ile 844 | engineered mutation |
| Tyr 846 | Ala 846 | engineered mutation |
| Pro 986 | Lys 986 | engineered mutation |
| Pro 987 | Val 987 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 9 |
| Total formula weight | 476112.4 | |
| Branched | Number of molecules | 15 |
| Total formula weight | 6366.0 | |
| Non-Polymers* | Number of molecules | 29 |
| Total formula weight | 6415.0 | |
| All* | Total formula weight | 488893.5 |
