7CXY
Structural insights into novel mechanisms of inhibition of the major b-carbonic anhydrase CafB from the pathogenic fungus Aspergillus fumigatus (zinc-bound form)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Carbonic anhydrase | polymer | 228 | 25998.6 | 2 | UniProt (A4DA32) Pfam (PF00484) In PDB | Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) | Carbonate dehydratase |
| 2 | A, B | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | water | water | 18.0 | 136 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 228 (UniProt: A4DA32)
| PDB | External Database | Details |
|---|---|---|
| Ala 159 | Tyr 159 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 51997.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 130.8 | |
| All* | Total formula weight | 52127.9 |
