7CXL
The ligand-free structure of human PPARgamma LBD S289C mutant in the presence of the SRC-1 coactivator peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Peroxisome proliferator-activated receptor gamma | polymer | 283 | 32296.4 | 1 | UniProt (P37231) Pfam (PF00104) | Homo sapiens (Human) | PPAR-gamma,Nuclear receptor subfamily 1 group C member 3 |
| 2 | B (B) | 16-mer peptide from Nuclear receptor coactivator 1 | polymer | 16 | 1905.2 | 1 | UniProt (Q15788) | Homo sapiens | |
| 3 | C (A) | MALONIC ACID | non-polymer | 104.1 | 1 | Chemie (MLA) | |||
| 4 | D (A) | water | water | 18.0 | 36 | Chemie (HOH) |
Sequence modifications
A: 195 - 477 (UniProt: P37231)
| PDB | External Database | Details |
|---|---|---|
| Cys 289 | Ser 317 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 34201.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 104.1 | |
| All* | Total formula weight | 34305.7 |
