7CVX

Crystal structure of Catechol o-methyl transferase (COMT) from Niastella koreensis

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	O-methyltransferase family 3	polymer	229	25128.6	2	UniProt (G8T6H8) Pfam (PF01596)	Niastella koreensis GR20-10
2	C, F (A, B)	S-ADENOSYL-L-HOMOCYSTEINE	non-polymer		384.4	2	Chemie (SAH)
3	D, G (A, B)	3,4-DIHYDROXYBENZOIC ACID	non-polymer		154.1	2	Chemie (DHB)
4	E, I (A, B)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
5	H (B)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
6	J, K (A, B)	water	water		18.0	291	Chemie (HOH)

Sequence modifications

A, B: 1 - 221 (UniProt: G8T6H8)

PDB	External Database	Details
Leu 222	-	expression tag
Glu 223	-	expression tag
His 224	-	expression tag
His 225	-	expression tag
His 226	-	expression tag
His 227	-	expression tag
His 228	-	expression tag
His 229	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	50257.3
Non-Polymers*	Number of molecules	7
	Total formula weight	1217.8
All*	Total formula weight	51475.0

*Water molecules are not included.