7CQF

Crystal structure of PSD-95 PDZ3 fused with ADAM22 C-terminal peptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Disks large homolog 4,Disintegrin and metalloproteinase domain-containing protein 22	polymer	150	16446.4	1	UniProt (P31016) UniProt (Q9P0K1) Pfam (PF00595)	Rattus norvegicus (Rat)	Postsynaptic density protein 95,PSD-95,Synapse-associated protein 90,SAP90,ADAM 22,Metalloproteinase-disintegrin ADAM22-3,Metalloproteinase-like,disintegrin-like,and cysteine-rich protein 2
2	B (A)	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
3	C (A)	CHOLINE ION	non-polymer		104.2	1	Chemie (CHT)
4	D, E, F, G (A)	1,2-ETHANEDIOL	non-polymer		62.1	4	Chemie (EDO)
5	H (A)	water	water		18.0	46	Chemie (HOH)

Sequence modifications

A: 309 - 422 (UniProt: P31016)

PDB	External Database	Details
Met 292	-	initiating methionine
Asn 293	-	expression tag
His 294	-	expression tag
Lys 295	-	expression tag
Val 296	-	expression tag
His 297	-	expression tag
His 298	-	expression tag
His 299	-	expression tag
His 300	-	expression tag
His 301	-	expression tag
His 302	-	expression tag
Ile 303	-	expression tag
Glu 304	-	expression tag
Gly 305	-	expression tag
Arg 306	-	expression tag
His 307	-	expression tag
Asn 308	-	expression tag
Gly 423	-	linker
Ser 424	-	linker
Ser 425	-	linker
Gly 426	-	linker

A: 427 - 441 (UniProt: Q9P0K1)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	16446.4
Non-Polymers*	Number of molecules	6
	Total formula weight	387.9
All*	Total formula weight	16834.3

*Water molecules are not included.