7CQ4
Crystal structure of Slx1-Slx4 in complex with 5'flap DNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | H | DNA (5'-D(*GP*GP*AP*TP*TP*AP*CP*AP*AP*CP*AP*GP*AP*T)-3') | polymer | 14 | 4312.8 | 1 | Saccharomyces cerevisiae | ||
| 2 | K | DNA (5'-D(*AP*GP*GP*AP*CP*AP*TP*CP*TP*TP*TP*GP*CP*C)-3') | polymer | 14 | 4255.8 | 1 | Saccharomyces cerevisiae | ||
| 3 | L | DNA (27-MER) | polymer | 27 | 8291.4 | 1 | Saccharomyces cerevisiae | ||
| 4 | A | Structure-specific endonuclease subunit SLX1 | polymer | 304 | 35884.6 | 1 | UniProt (A6ZLG6) Pfam (PF01541) Pfam (PF21202) UniProt (by SIFTS) (P38324) In PDB | Saccharomyces cerevisiae (strain YJM789) (Baker's yeast) | |
| 5 | B | SLX4 isoform 1 | polymer | 151 | 17144.5 | 1 | UniProt (A0A6A5PU22) Pfam (PF09494) UniProt (by SIFTS) (Q12098) In PDB | Saccharomyces cerevisiae (Baker's yeast) | |
| 6 | A | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 7 | water | water | 18.0 | 12 | Chemie (HOH) |
Sequence modifications
A: 1 - 304 (UniProt: A6ZLG6)
B: 610 - 748 (UniProt: A0A6A5PU22)
| PDB | External Database | Details |
|---|---|---|
| Phe 17 | Tyr 17 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Met 598 | - | initiating methionine |
| Gly 599 | - | expression tag |
| Ser 600 | - | expression tag |
| Ser 601 | - | expression tag |
| His 602 | - | expression tag |
| His 603 | - | expression tag |
| His 604 | - | expression tag |
| His 605 | - | expression tag |
| His 606 | - | expression tag |
| His 607 | - | expression tag |
| Ser 608 | - | expression tag |
| Gln 609 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 69889.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 130.8 | |
| All* | Total formula weight | 70019.9 |
