7CPD
Crystal structure of T2R-TTL-(+)-6-Br-JP18 complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Tubulin alpha-1B chain | polymer | 451 | 50204.4 | 2 | UniProt (P81947) Pfam (PF00091) Pfam (PF03953) | Bos taurus (Bovine) | Alpha-tubulin ubiquitous,Tubulin K-alpha-1,Tubulin alpha-ubiquitous chain |
| 2 | B, D (B, D) | Tubulin beta-2B chain | polymer | 445 | 49999.9 | 2 | UniProt (Q6B856) Pfam (PF00091) Pfam (PF03953) | Bos taurus (Bovine) | |
| 3 | E (E) | Stathmin-4 | polymer | 189 | 22125.3 | 1 | UniProt (Q9H169) Pfam (PF00836) | Homo sapiens (Human) | Stathmin-like protein B3,RB3 |
| 4 | F (F) | Tubulin tyrosine ligase | polymer | 378 | 43549.6 | 1 | UniProt (E1BQ43) | Gallus gallus (Chicken) | |
| 5 | G, P (A, C) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 2 | Chemie (GTP) | |||
| 6 | H, K, Q (A, B, C) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
| 7 | I, L, R (A, B, C) | CALCIUM ION | non-polymer | 40.1 | 3 | Chemie (CA) | |||
| 8 | J, S (B, D) | (6R)-6-[(6-bromanyl-1H-indol-3-yl)methyl]-6,7,8,9-tetrahydrobenzo[7]annulen-5-one | non-polymer | 368.3 | 2 | Chemie (G9U) | |||
| 9 | M, T (B, D) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 2 | Chemie (GDP) | |||
| 10 | N (B) | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 1 | Chemie (MES) | |||
| 11 | O (C) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 12 | U, V, W, X, Y... (A, B, C, D, E...) | water | water | 18.0 | 340 | Chemie (HOH) |
Sequence modifications
E: -43 - 145 (UniProt: Q9H169)
| PDB | External Database | Details |
|---|---|---|
| Ser -19 | Ala 25 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 266083.6 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 3149.8 | |
| All* | Total formula weight | 269233.4 |
