7CO1
Crystal structure of SMAD2 in complex with wild-type CBP
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C, E | Mothers against decapentaplegic homolog 2 | polymer | 208 | 23481.6 | 3 | UniProt (Q15796) Pfam (PF03166) In PDB | Homo sapiens (Human) | Mothers against DPP homolog 2,JV18-1,Mad-related protein 2,hMAD-2,SMAD family member 2,hSMAD2 |
2 | B, D, F | CREB-binding protein | polymer | 28 | 3137.3 | 3 | UniProt (Q92793) In PDB | Homo sapiens (Human) | Histone lysine acetyltransferase CREBBP,Protein-lysine acetyltransferase CREBBP |
Sequence modifications
A, C, E: 262 - 467 (UniProt: Q15796)
B, D, F: 1951 - 1973 (UniProt: Q92793)
PDB | External Database | Details |
---|---|---|
Gly 260 | - | expression tag |
Pro 261 | - | expression tag |
Glu 465 | Ser 465 | engineered mutation |
Glu 467 | Ser 467 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Gly 1950 | - | expression tag |
Ser 1974 | - | expression tag |
Asp 1975 | - | expression tag |
Glu 1976 | - | expression tag |
Asp 1977 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 79856.7 | |
All* | Total formula weight | 79856.7 |