7CM2

The Crystal Structure of human USP7 USP domain from Biortus

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Ubiquitin carboxyl-terminal hydrolase 7	polymer	370	43017.5	2	UniProt (Q93009) Pfam (PF00443)	Homo sapiens (Human)	Deubiquitinating enzyme 7,Herpesvirus-associated ubiquitin-specific protease,Ubiquitin thioesterase 7,Ubiquitin-specific-processing protease 7
2	C, D, E, F, G... (A, B)	GLYCEROL	non-polymer		92.1	8	Chemie (GOL)
3	K, L (A, B)	water	water		18.0	252	Chemie (HOH)

Sequence modifications

A, B: 208 - 560 (UniProt: Q93009)

PDB	External Database	Details
Met 191	-	initiating methionine
Gly 192	-	expression tag
Gly 193	-	expression tag
Ser 194	-	expression tag
His 195	-	expression tag
His 196	-	expression tag
His 197	-	expression tag
His 198	-	expression tag
His 199	-	expression tag
His 200	-	expression tag
Glu 201	-	expression tag
Asn 202	-	expression tag
Leu 203	-	expression tag
Tyr 204	-	expression tag
Phe 205	-	expression tag
Gln 206	-	expression tag
Gly 207	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	86035.0
Non-Polymers*	Number of molecules	8
	Total formula weight	736.8
All*	Total formula weight	86771.7

*Water molecules are not included.