7CKO
Cryo-EM structure of the human MCT1/Basigin-2 complex in the presence of anti-cancer drug candidate 7ACC2 in the inward-open conformation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Monocarboxylate transporter 1 | polymer | 500 | 53992.9 | 1 | UniProt (P53985) Pfam (PF07690) In PDB | Homo sapiens (Human) | MCT 1,Solute carrier family 16 member 1 |
| 2 | B | Basigin | polymer | 269 | 29254.9 | 1 | UniProt (P35613) Pfam (PF13927) In PDB | Homo sapiens (Human) | 5F7,Collagenase stimulatory factor,Extracellular matrix metalloproteinase inducer,EMMPRIN,Leukocyte activation antigen M6,OK blood group antigen,Tumor cell-derived collagenase stimulatory factor,TCSF |
| 3 | A | 7-[methyl-(phenylmethyl)amino]-2-oxidanylidene-chromene-3-carboxylic acid | non-polymer | 309.3 | 1 | Chemie (G5L) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 83247.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 309.3 | |
| All* | Total formula weight | 83557.1 |
