7CJG

Structural and kinetic characterization of Porphyromonas gingivalis glutaminyl cyclase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Glutamine cyclotransferase-related protein	polymer	333	36565.4	2	UniProt (Q7MT37) Pfam (PF04389)	Porphyromonas gingivalis (strain ATCC BAA-308 / W83)
2	C, I (A, B)	5,6-DIMETHYLBENZIMIDAZOLE	non-polymer		146.2	2	Chemie (DMD)
3	D, K (A, B)	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
4	E, F, J (A, B)	NITRATE ION	non-polymer		62.0	3	Chemie (NO3)
5	G, L (A, B)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
6	H, M (A, B)	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
7	N, O (A, B)	water	water		18.0	333	Chemie (HOH)

Sequence modifications

A, B: 22 - 333 (UniProt: Q7MT37)

PDB	External Database	Details
Met 1	-	initiating methionine
Gly 2	-	expression tag
Ser 3	-	expression tag
Ser 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
His 7	-	expression tag
His 8	-	expression tag
His 9	-	expression tag
His 10	-	expression tag
Ser 11	-	expression tag
Ser 12	-	expression tag
Gly 13	-	expression tag
Leu 14	-	expression tag
Val 15	-	expression tag
Pro 16	-	expression tag
Arg 17	-	expression tag
Gly 18	-	expression tag
Ser 19	-	expression tag
His 20	-	expression tag
Met 21	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	73130.8
Non-Polymers*	Number of molecules	11
	Total formula weight	842.0
All*	Total formula weight	73972.8

*Water molecules are not included.