7CJA
Crystal structure of TTK kinase domain in complex with compound 28
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Dual specificity protein kinase TTK | polymer | 283 | 33021.5 | 1 | UniProt (P33981) Pfam (PF00069) In PDB | Homo sapiens (Human) | Phosphotyrosine picked threonine-protein kinase,PYT |
2 | A | 4-(cyclopentylmethylamino)-2-[[2-methoxy-4-(2-oxidanylidenepyrrolidin-1-yl)phenyl]amino]-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile | non-polymer | 445.5 | 1 | Chemie (G0U) | |||
3 | water | water | 18.0 | 13 | Chemie (HOH) |
Sequence modifications
A: 515 - 795 (UniProt: P33981)
PDB | External Database | Details |
---|---|---|
Leu 796 | - | expression tag |
Glu 797 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 33021.5 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 445.5 | |
All* | Total formula weight | 33467.0 |