7CJ1
The crystal structure of FXIa serine protease domain in complex with benzamidine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Coagulation factor XI | polymer | 236 | 26714.3 | 4 | UniProt (P03951) Pfam (PF00089) | Homo sapiens (Human) | FXI,Plasma thromboplastin antecedent,PTA |
| 2 | E, F, G, H (A, B, C, D) | BENZAMIDINE | non-polymer | 120.2 | 4 | Chemie (BEN) | |||
| 3 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 142 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 16 - 243 (UniProt: P03951)
| PDB | External Database | Details |
|---|---|---|
| Gln 73 | Asn 450 | conflict |
| Gln 113 | Asn 491 | conflict |
| Ser 123 | Cys 500 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 106857.3 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 480.6 | |
| All* | Total formula weight | 107338.0 |
