7CIB
Crystal structure of P.aeruginosa LpxC in complex with inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | UDP-3-O-acyl-N-acetylglucosamine deacetylase | polymer | 299 | 33146.6 | 1 | UniProt (P47205) Pfam (PF03331) | Pseudomonas aeruginosa PAO1 | UDP-3-O-acyl-GlcNAc deacetylase,UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase |
| 2 | B (A) | 2-oxidanyl-4-phenyl-benzoic acid | non-polymer | 214.2 | 1 | Chemie (FYR) | |||
| 3 | C, D, E (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 3 | Chemie (DMS) | |||
| 4 | F (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 5 | G (A) | water | water | 18.0 | 213 | Chemie (HOH) |
Sequence modifications
A: 1 - 299 (UniProt: P47205)
| PDB | External Database | Details |
|---|---|---|
| Ser 40 | Cys 40 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33146.6 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 514.0 | |
| All* | Total formula weight | 33660.6 |
