7CI9
Crystal structure of P.aeruginosa LpxC in complex with inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | UDP-3-O-acyl-N-acetylglucosamine deacetylase | polymer | 299 | 33146.6 | 1 | UniProt (P47205) Pfam (PF03331) | Pseudomonas aeruginosa PAO1 | UDP-3-O-acyl-GlcNAc deacetylase,UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase |
| 2 | B (A) | 2-azanyl-2-[[4-[2-[3-[[2-[(1S)-1-oxidanylethyl]imidazol-1-yl]methyl]-1,2-oxazol-5-yl]ethynyl]phenoxy]methyl]propane-1,3-diol | non-polymer | 412.4 | 1 | Chemie (FYL) | |||
| 3 | C (A) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 4 | D, E, F, G, H... (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 6 | Chemie (EDO) | |||
| 5 | J (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 6 | K (A) | water | water | 18.0 | 272 | Chemie (HOH) |
Sequence modifications
A: 1 - 299 (UniProt: P47205)
| PDB | External Database | Details |
|---|---|---|
| Ser 40 | Cys 40 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33146.6 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 945.2 | |
| All* | Total formula weight | 34091.8 |
