7CHT
Crystal structure of TTK kinase domain in complex with compound 30
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Dual specificity protein kinase TTK | polymer | 282 | 32892.4 | 1 | UniProt (P33981) Pfam (PF00069) In PDB | Homo sapiens (Human) | Phosphotyrosine picked threonine-protein kinase,PYT |
| 2 | A | 2-[[2-methoxy-4-(2-oxidanylidenepyrrolidin-1-yl)phenyl]amino]-4-(oxan-4-ylamino)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile | non-polymer | 447.5 | 1 | Chemie (FZO) | |||
| 3 | A | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 4 | water | water | 18.0 | 19 | Chemie (HOH) |
Sequence modifications
A: 515 - 795 (UniProt: P33981)
| PDB | External Database | Details |
|---|---|---|
| Leu 796 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 32892.4 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 496.1 | |
| All* | Total formula weight | 33388.5 |
