7CGW
Complex structure of PD-1 and tislelizumab Fab
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, H) | Heavy chain of tislelizumab Fab | polymer | 228 | 24477.3 | 2 | Homo sapiens | ||
| 2 | B, E (B, L) | Light chain of tislelizumab Fab | polymer | 214 | 23549.1 | 2 | Homo sapiens | ||
| 3 | C, F (C, P) | Programmed cell death protein 1 | polymer | 151 | 16979.9 | 2 | UniProt (Q15116) Pfam (PF07686) | Homo sapiens (Human) | hPD-1 |
| 4 | G, H, I, J, K... (C, P) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 7 | Chemie (NAG) |
Sequence modifications
C, P: 25 - 169 (UniProt: Q15116)
| PDB | External Database | Details |
|---|---|---|
| Glu 170 | - | expression tag |
| Asn 171 | - | expression tag |
| Leu 172 | - | expression tag |
| Tyr 173 | - | expression tag |
| Phe 174 | - | expression tag |
| Gln 175 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 130012.6 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1548.5 | |
| All* | Total formula weight | 131561.1 |
