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7CFQ

Crystal structure of WDR5 in complex with H3K4me3Q5ser peptide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
WD repeat-containing protein 5polymer33436635.41UniProt (P61964)
Pfam (PF00400)
Homo sapiens (Human)BMP2-induced 3-kb gene protein
2B
(B)
H3K4me3Q5ser peptidepolymer141495.71UniProt (by SIFTS) (P68431)Homo sapiens
3C
(A)
GLYCEROLnon-polymer92.11Chemie (GOL)
4D
(A)
1,2-ETHANEDIOLnon-polymer62.11Chemie (EDO)
5E
(B)
SEROTONINnon-polymer176.21Chemie (SRO)
6F, G
(A, B)
waterwater18.0179Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight38131.1
Non-Polymers*Number of molecules3
Total formula weight330.4
All*Total formula weight38461.5
*Water molecules are not included.

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PDB entries from 2025-06-18

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