7CF9

Structure of RyR1 (Ca2+/CHL)

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E, G (A, C, E, G)	Ryanodine receptor 1,RyR1	polymer	5037	539836.9	4	UniProt (P11716) Pfam (PF08709) Pfam (PF01365) Pfam (PF02026) Pfam (PF08454) Pfam (PF06459) Pfam (PF00520) Pfam (PF02815) Pfam (PF00622) Pfam (PF21119)	Oryctolagus cuniculus (Rabbit)	RyR1,Skeletal muscle calcium release channel,Skeletal muscle ryanodine receptor,Skeletal muscle-type ryanodine receptor,Type 1 ryanodine receptor
2	B, D, F, H (B, D, F, H)	Peptidyl-prolyl cis-trans isomerase FKBP1B	polymer	107	11667.3	4	UniProt (P68106) Pfam (PF00254)	Homo sapiens (Human)	PPIase FKBP1B,12.6 kDa FK506-binding protein,FKBP-12.6,FK506-binding protein 1B,FKBP-1B,Immunophilin FKBP12.6,Rotamase,h-FKBP-12
3	I, L, O, R (A, C, E, G)	CALCIUM ION	non-polymer		40.1	4	Chemie (CA)
4	J, M, P, S (A, C, E, G)	ZINC ION	non-polymer		65.4	4	Chemie (ZN)
5	K, N, Q, T (A, C, E, G)	5-bromanyl-N-[4-chloranyl-2-methyl-6-(methylcarbamoyl)phenyl]-2-(3-chloranylpyridin-2-yl)pyrazole-3-carboxamide	non-polymer		483.1	4	Chemie (F0U)

Sequence modifications

A, C, E, G: 1 - 2634 (UniProt: P11716)
A, C, E, G: 2635 - 2740 (PDB: 7CF9)
A, C, E, G: 2741 - 2939 (UniProt: P11716)
A, C, E, G: 2940 - 3622 (PDB: 7CF9)
A, C, E, G: 3623 - 4253 (UniProt: P11716)
A, C, E, G: 4254 - 4540 (PDB: 7CF9)
A, C, E, G: 4541 - 5037 (UniProt: P11716)

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	2206017.0
Non-Polymers*	Number of molecules	12
	Total formula weight	2354.5
All*	Total formula weight	2208371.5

*Water molecules are not included.