7CBH
Crystal structure of threonyl-tRNA synthetase (ThrRS) from Salmonella enterica in complex with an inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Threonine--tRNA ligase | polymer | 411 | 47964.5 | 2 | UniProt (V7II86) Pfam (PF00587) Pfam (PF03129) | Salmonella enterica subsp. enterica serovar Cubana str. 76814 | Threonyl-tRNA synthetase,ThrRS |
| 2 | C (A) | [(E)-4-(7-bromanyl-6-chloranyl-4-oxidanylidene-quinazolin-3-yl)but-2-enyl] (2S,3R)-2-azanyl-3-oxidanyl-butanoate | non-polymer | 430.7 | 1 | Chemie (FQR) | |||
| 3 | D, E (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | F, G (A, B) | water | water | 18.0 | 474 | Chemie (HOH) |
Sequence modifications
A, B: 242 - 642 (UniProt: V7II86)
| PDB | External Database | Details |
|---|---|---|
| Met 240 | - | expression tag |
| Gly 241 | - | expression tag |
| Leu 643 | - | expression tag |
| Glu 644 | - | expression tag |
| His 645 | - | expression tag |
| His 646 | - | expression tag |
| His 647 | - | expression tag |
| His 648 | - | expression tag |
| His 649 | - | expression tag |
| His 650 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 95929.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 561.5 | |
| All* | Total formula weight | 96490.5 |
