7CAI
SARS-CoV-2 S trimer with two RBDs in the open state and complexed with two H014 Fab
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C | Spike glycoprotein | polymer | 1208 | 133865.4 | 3 | UniProt (P0DTC2) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601) In PDB | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) | S glycoprotein,E2,Peplomer protein |
| 2 | D, F | Light chain of H014 Fab | polymer | 210 | 23289.0 | 2 | Homo sapiens | ||
| 3 | E, G | Heavy chain of H014 Fab | polymer | 223 | 23823.6 | 2 | Homo sapiens | ||
| 4 | H, I, J, K, L... | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 15 | In PDB GlyTouCan (G42666HT) | |||
| 5 | A, B, C | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 30 | Chemie (NAG) |
Sequence modifications
A, B, C: 1 - 1208 (UniProt: P0DTC2)
| PDB | External Database | Details |
|---|---|---|
| Gly 682 | Arg 682 | engineered mutation |
| Ser 683 | Arg 683 | engineered mutation |
| Ser 685 | Arg 685 | engineered mutation |
| Met 835 | Lys 835 | engineered mutation |
| Met 844 | Ile 844 | engineered mutation |
| Tyr 846 | Ala 846 | engineered mutation |
| Pro 986 | Lys 986 | engineered mutation |
| Pro 987 | Val 987 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 7 |
| Total formula weight | 495821.3 | |
| Branched | Number of molecules | 15 |
| Total formula weight | 6366.0 | |
| Non-Polymers* | Number of molecules | 30 |
| Total formula weight | 6636.2 | |
| All* | Total formula weight | 508823.6 |
