7CA0
Crystal structure of dihydroorotase in complex with 5-fluoroorotic acid from Saccharomyces cerevisiae
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Dihydroorotase | polymer | 372 | 41478.4 | 4 | UniProt (P20051) Pfam (PF04909) In PDB | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | DHOase |
| 2 | A, B, C, D | ZINC ION | non-polymer | 65.4 | 8 | Chemie (ZN) | |||
| 3 | A, B, C, D | 5-FLUORO-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID | non-polymer | 174.1 | 4 | Chemie (FOT) | |||
| 4 | water | water | 18.0 | 186 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 364 (UniProt: P20051)
| PDB | External Database | Details |
|---|---|---|
| Leu 365 | - | expression tag |
| Glu 366 | - | expression tag |
| His 367 | - | expression tag |
| His 368 | - | expression tag |
| His 369 | - | expression tag |
| His 370 | - | expression tag |
| His 371 | - | expression tag |
| His 372 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 165913.4 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1219.6 | |
| All* | Total formula weight | 167133.0 |
