7C8V
Structure of sybody SR4 in complex with the SARS-CoV-2 S Receptor Binding domain (RBD)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Synthetic nanobody SR4 | polymer | 144 | 15985.5 | 1 | synthetic construct | ||
| 2 | B | Spike protein S1 | polymer | 213 | 23747.6 | 1 | UniProt (P0DTC2) Pfam (PF09408) In PDB | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) | S glycoprotein,E2,Peplomer protein,Spike glycoprotein |
| 3 | A, B | GLYCEROL | non-polymer | 92.1 | 8 | Chemie (GOL) | |||
| 4 | B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 5 | water | water | 18.0 | 238 | Chemie (HOH) |
Sequence modifications
B: 330 - 531 (UniProt: P0DTC2)
| PDB | External Database | Details |
|---|---|---|
| Ala 327 | - | expression tag |
| Gly 328 | - | expression tag |
| Ser 329 | - | expression tag |
| Gly 532 | - | expression tag |
| Thr 533 | - | expression tag |
| Leu 534 | - | expression tag |
| Glu 535 | - | expression tag |
| Val 536 | - | expression tag |
| Leu 537 | - | expression tag |
| Phe 538 | - | expression tag |
| Gln 539 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 39733.2 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 958.0 | |
| All* | Total formula weight | 40691.1 |
