7C3S
Crystal structure of NE0047 (E143D) mutant in complex with 8-azaguanine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Cytidine and deoxycytidylate deaminase zinc-binding region | polymer | 195 | 20428.3 | 2 | UniProt (Q82Y41) Pfam (PF00383) | Nitrosomonas europaea (strain ATCC 19718 / CIP 103999 / KCTC 2705 / NBRC 14298) | Guanine deaminase |
| 2 | C, F (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | D, E, H (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 4 | G (B) | 5-AMINO-1H-[1,2,3]TRIAZOLO[4,5-D]PYRIMIDIN-7-OL | non-polymer | 152.1 | 1 | Chemie (AZG) | |||
| 5 | I (B) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 6 | J, K (A, B) | water | water | 18.0 | 181 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 193 (UniProt: Q82Y41)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| His 0 | - | expression tag |
| Asp 143 | Glu 143 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 40856.6 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 561.2 | |
| All* | Total formula weight | 41417.8 |
