7C2X

Crystal Structure of Glycyrrhiza uralensis UGT73P12 complexed with glycyrrhetinic acid 3-O-monoglucuronide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Glycosyltransferase	polymer	514	57840.8	1	UniProt (A0A5A4WN00)	Glycyrrhiza uralensis (Chinese licorice)
2	B (A)	URIDINE-5'-DIPHOSPHATE	non-polymer		404.2	1	Chemie (UDP) PubChem (25323044) PubChem (25323048) PubChem (44298965) PubChem (57448939) PubChem (53486216) PubChem (60098857) PubChem (91746160) PubChem (92332560) PubChem (92332561) PubChem (92332562) PubChem (92332563) PubChem (93088131) PubChem (93630083) PubChem (1158) PubChem (6031) PubChem (3084486) PubChem (6101632) PubChem (6604175) PubChem (11811538) PubChem (12049241)
3	C (A)	(2~{S},3~{S},4~{S},5~{R},6~{R})-6-[[(3~{S},4~{a}~{R},6~{a}~{R},6~{b}~{S},8~{a}~{S},11~{S},12~{a}~{R},14~{a}~{R},14~{b}~{S})-11-carboxy-4,4,6~{a},6~{b},8~{a},11,14~{b}-heptamethyl-14-oxidanylidene-2,3,4~{a},5,6,7,8,9,10,12,12~{a},14~{a}-dodecahydro-1~{H}-picen-3-yl]oxy]-3,4,5-tris(oxidanyl)oxane-2-carboxylic acid	non-polymer		646.8	1	Chemie (FJL) PubChem (25029962) PubChem (49822197) PubChem (53883070) PubChem (14312747) PubChem (53883072) PubChem (129905503) PubChem (154828373) PubChem (169434388) PubChem (59336512) PubChem (102510758) PubChem (161800) PubChem (133587387) PubChem (145993192) PubChem (154582022) PubChem (174028234)
4	D (A)	water	water		18.0	303	Chemie (HOH)

Sequence modifications

A: 1 - 506 (UniProt: A0A5A4WN00)

PDB	External Database	Details
Leu 507	-	expression tag
Glu 508	-	expression tag
His 509	-	expression tag
His 510	-	expression tag
His 511	-	expression tag
His 512	-	expression tag
His 513	-	expression tag
His 514	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	57840.8
Non-Polymers*	Number of molecules	2
	Total formula weight	1051.0
All*	Total formula weight	58891.8

*Water molecules are not included.