7C2W

Crystal Structure of IRAK4 kinase in complex with a small molecule inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Interleukin-1 receptor-associated kinase 4	polymer	296	33416.8	4	UniProt (Q9NWZ3) Pfam (PF07714)	Homo sapiens (Human)	IRAK-4,Renal carcinoma antigen NY-REN-64
2	E, F, G, H (A, B, C, D)	N-(2-morpholin-4-yl-1,3-benzoxazol-6-yl)-6-pyridin-4-yl-pyridine-2-carboxamide	non-polymer		401.4	4	Chemie (FJ9)
3	I, J, K, L (A, B, C, D)	water	water		18.0	164	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	133667.1
Non-Polymers*	Number of molecules	4
	Total formula weight	1605.7
All*	Total formula weight	135272.7

*Water molecules are not included.