7BXT
The cryo-EM structure of CENP-A nucleosome in complex with CENP-C peptide and CENP-N N-terminal domain
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, E | Histone H3,Histone H3-like centromeric protein A | polymer | 144 | 16372.2 | 2 | UniProt (Q6XXM1) Pfam (PF00125) UniProt (by SIFTS) (P84229) In PDB | Gallus gallus (Chicken) | Centromere protein A,GgCENP-A |
2 | B, F | Histone H4 | polymer | 106 | 11676.7 | 2 | UniProt (P62805) Pfam (PF15511) In PDB | Homo sapiens (Human) | |
3 | C, G | Histone H2A type 1-B/E | polymer | 133 | 14447.8 | 2 | UniProt (P04908) Pfam (PF00125) Pfam (PF16211) In PDB | Homo sapiens (Human) | Histone H2A.2,Histone H2A/a,Histone H2A/m |
4 | D, H | Histone H2B type 2-E | polymer | 129 | 14233.5 | 2 | UniProt (Q16778) Pfam (PF00125) In PDB | Homo sapiens (Human) | H2B-clustered histone 21,Histone H2B-GL105,Histone H2B.q,H2B/q |
5 | I | DNA (145-mer) | polymer | 145 | 44529.4 | 1 | synthetic construct | ||
6 | J | DNA (145-mer) | polymer | 145 | 44982.6 | 1 | synthetic construct | ||
7 | K, L | CENP-C | polymer | 41 | 4932.8 | 2 | UniProt (O57392) In PDB | Gallus gallus | Centromere protein CENP-C |
8 | M, N | Maltodextrin-binding protein,Centromere protein N | polymer | 630 | 71519.6 | 2 | UniProt (Q1T765) Pfam (PF01547) Pfam (PF05238) UniProt (by SIFTS) (P0AEX9) In PDB | unidentified cloning vector | CENP-N |
Sequence modifications
A, E: -2 - 63 (PDB: 7BXT)
A, E: 64 - 141 (UniProt: Q6XXM1)
B, F: 1 - 102 (UniProt: P62805)
C, G: 1 - 129 (UniProt: P04908)
D, H: 0 - 125 (UniProt: Q16778)
M, N: -410 - 0 (PDB: 7BXT)
M, N: 1 - 211 (UniProt: Q1T765)
A, E: 64 - 141 (UniProt: Q6XXM1)
B, F: 1 - 102 (UniProt: P62805)
PDB | External Database | Details |
---|---|---|
Gly -3 | - | expression tag |
Ser -2 | - | expression tag |
His -1 | - | expression tag |
Met 0 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly -3 | - | expression tag |
Ser -2 | - | expression tag |
His -1 | - | expression tag |
Met 0 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly -3 | - | expression tag |
Ser -2 | - | expression tag |
His -1 | - | expression tag |
M, N: 1 - 211 (UniProt: Q1T765)
PDB | External Database | Details |
---|---|---|
Asp 212 | - | expression tag |
Pro 213 | - | expression tag |
His 214 | - | expression tag |
His 215 | - | expression tag |
His 216 | - | expression tag |
His 217 | - | expression tag |
His 218 | - | expression tag |
His 219 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 14 |
Total formula weight | 355877.5 | |
All* | Total formula weight | 355877.5 |