7BUJ

mcGAS bound with pppGpG

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Cyclic GMP-AMP synthase	polymer	447	51649.4	2	UniProt (Q8C6L5) Pfam (PF03281) Pfam (PF20266)	Mus musculus (Mouse)	m-cGAS,2'3'-cGAMP synthase,Mab-21 domain-containing protein 1
2	C, H (A, B)	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
3	D, I (A, B)	GUANOSINE-5'-TRIPHOSPHATE	non-polymer		523.2	2	Chemie (GTP)
4	E, F, J, K (A, B)	MANGANESE (II) ION	non-polymer		54.9	4	Chemie (MN)
5	G, L (A, B)	GUANOSINE-5'-MONOPHOSPHATE	non-polymer		363.2	2	Chemie (5GP)
6	M, N (A, B)	water	water		18.0	176	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	103298.9
Non-Polymers*	Number of molecules	10
	Total formula weight	2123.4
All*	Total formula weight	105422.2

*Water molecules are not included.