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7BSK

Crystal structure of human ME2 R67Q mutant

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
NAD-dependent malic enzyme, mitochondrialpolymer56663476.92UniProt (P23368)
Pfam (PF00390)
Pfam (PF03949)
Homo sapiens (Human)NAD-ME,Malic enzyme 2
2C, D, E, F
(A, B)
NICOTINAMIDE-ADENINE-DINUCLEOTIDEnon-polymer663.44Chemie (NAD)
3G, H
(A, B)
waterwater18.093Chemie (HOH)
Sequence modifications
A, B: 20 - 584 (UniProt: P23368)
PDBExternal DatabaseDetails
Met 19-initiating methionine
Gln 67Arg 67engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight126953.8
Non-Polymers*Number of molecules4
Total formula weight2653.7
All*Total formula weight129607.5
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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