7BR3

Crystal structure of the protein 1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Gonadotropin-releasing hormone receptor,GlgA glycogen synthase,Gonadotropin-releasing hormone receptor	polymer	528	60283.4	1	UniProt (P30968) UniProt (Q9V2J8) Pfam (PF00001) Pfam (PF13692)	Homo sapiens (Human)	GnRH-R,Glycogen synthase,GnRH-R
2	B (A)	(2R)-2,3-dihydroxypropyl dodecanoate	non-polymer		274.4	1	Chemie (1QW)
3	C, D (A)	(2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate	non-polymer		356.5	2	Chemie (OLC)
4	E, F, G, H, I... (A)	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	6	Chemie (PEG)
5	K (A)	FORMIC ACID	non-polymer		46.0	1	Chemie (FMT)
6	L (A)	4-[[(1R)-2-[5-(2-fluoranyl-3-methoxy-phenyl)-3-[[2-fluoranyl-6-(trifluoromethyl)phenyl]methyl]-4-methyl-2,6-bis(oxidanylidene)pyrimidin-1-yl]-1-phenyl-ethyl]amino]butanoic acid	non-polymer		631.6	1	Chemie (F5O)

Sequence modifications

A: 1 - 242 (UniProt: P30968)

PDB	External Database	Details
Asp -7	-	expression tag
Tyr -6	-	expression tag
Lys -5	-	expression tag
Asp -4	-	expression tag
Asp -3	-	expression tag
Asp -2	-	expression tag
Asp -1	-	expression tag
Ala 0	-	expression tag
Lys 128	Pro 128	engineered mutation

A: 1001 - 1196 (UniProt: Q9V2J8)
A: 257 - 328 (UniProt: P30968)

PDB	External Database	Details
His 329	-	expression tag
His 330	-	expression tag
His 331	-	expression tag
His 332	-	expression tag
His 333	-	expression tag
His 334	-	expression tag
His 335	-	expression tag
His 336	-	expression tag
His 337	-	expression tag
His 338	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	60283.4
Non-Polymers*	Number of molecules	11
	Total formula weight	2301.8
All*	Total formula weight	62585.2

*Water molecules are not included.