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7BPZ

X-ray structure of human PPARalpha ligand binding domain-bezafibrate-SRC1 coactivator peptide co-crystals obtained by soaking

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C
(A, C)
Peroxisome proliferator-activated receptor alphapolymer27330856.12UniProt (Q07869)
Pfam (PF00104)
Homo sapiens
2B, D
(B, D)
15-meric peptide from Nuclear receptor coactivator 1polymer151848.22UniProt (Q15788)Homo sapiens
3E, F
(A, C)
2-[P-[2-P-CHLOROBENZAMIDO)ETHYL]PHENOXY]-2-METHYLPROPIONIC ACIDnon-polymer361.82Chemie (PEM)
4G, H
(A, C)
waterwater18.08Chemie (HOH)
Sequence modifications
A, C: 200 - 468 (UniProt: Q07869)
PDBExternal DatabaseDetails
Gly 196-expression tag
Ser 197-expression tag
His 198-expression tag
Met 199-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight65408.5
Non-Polymers*Number of molecules2
Total formula weight723.6
All*Total formula weight66132.1
*Water molecules are not included.

247947

PDB entries from 2026-01-21

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