7BOT
Human SIRT2 in complex with myristoyl thiourea inhibitor, No.23
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | NAD-dependent protein deacetylase sirtuin-2 | polymer | 293 | 33201.2 | 1 | UniProt (Q8IXJ6) Pfam (PF02146) | Homo sapiens (Human) | Regulatory protein SIR2 homolog 2,SIR2-like protein 2 |
| 2 | B (B) | myristoyl thiourea inhibitor, No.23 | polymer | 5 | 521.6 | 1 | BIRD (PRD_002360) | synthetic construct | |
| 3 | C (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | D (B) | N-dodecylmethanethioamide | non-polymer | 229.4 | 1 | BIRD (PRD_002360) Chemie (F4R) | |||
| 5 | E, F (A, B) | water | water | 18.0 | 106 | Chemie (HOH) |
Sequence modifications
A: 52 - 356 (UniProt: Q8IXJ6)
| PDB | External Database | Details |
|---|---|---|
| - | Gln 292 | deletion |
| - | Ser 293 | deletion |
| - | Asp 294 | deletion |
| - | Pro 295 | deletion |
| - | Phe 296 | deletion |
| - | Leu 297 | deletion |
| - | Gly 298 | deletion |
| - | Met 299 | deletion |
| - | Ile 300 | deletion |
| - | Met 301 | deletion |
| - | Gly 302 | deletion |
| - | Leu 303 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 33722.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 294.8 | |
| All* | Total formula weight | 34017.7 |
