7BO1

Notum Fragment_274 [(4-fluorophenyl)amino]thiourea

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Palmitoleoyl-protein carboxylesterase NOTUM	polymer	382	43438.0	1	UniProt (Q6P988) Pfam (PF03283)	Homo sapiens (Human)	hNOTUM
2	B, D, E, F, G... (A)	SULFATE ION	non-polymer		96.1	6	Chemie (SO4)
3	C (A)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
4	I (A)	1,2-ETHANEDIOL	non-polymer		62.1	1	Chemie (EDO)
5	J, K, L (A)	1-[(4-fluorophenyl)amino]thiourea	non-polymer		185.2	3	Chemie (U5Z)
6	M, N, O (A)	DIMETHYL SULFOXIDE	non-polymer		78.1	3	Chemie (DMS)
7	P (A)	water	water		18.0	133	Chemie (HOH)

Sequence modifications

A: 81 - 451 (UniProt: Q6P988)

PDB	External Database	Details
Glu 78	-	expression tag
Thr 79	-	expression tag
Gly 80	-	expression tag
Ser 330	Cys 330	engineered mutation
Gly 452	-	expression tag
Thr 453	-	expression tag
His 454	-	expression tag
His 455	-	expression tag
His 456	-	expression tag
His 457	-	expression tag
His 458	-	expression tag
His 459	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	43438.0
Non-Polymers*	Number of molecules	14
	Total formula weight	1520.6
All*	Total formula weight	44958.6

*Water molecules are not included.