7BKO
Crystal structure of CHK1 complex with compound 9
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Serine/threonine-protein kinase Chk1 | polymer | 297 | 34148.1 | 1 | UniProt (O14757) Pfam (PF00069) | Homo sapiens (Human) | CHK1 checkpoint homolog,Cell cycle checkpoint kinase,Checkpoint kinase-1 |
| 2 | B (A) | 1H-pyrazolo[3,4-d]pyrimidin-4-amine | non-polymer | 135.1 | 1 | Chemie (TVW) | |||
| 3 | C (A) | water | water | 18.0 | 212 | Chemie (HOH) |
Sequence modifications
A: 1 - 289 (UniProt: O14757)
| PDB | External Database | Details |
|---|---|---|
| His 290 | - | expression tag |
| His 291 | - | expression tag |
| His 292 | - | expression tag |
| His 293 | - | expression tag |
| His 294 | - | expression tag |
| His 295 | - | expression tag |
| His 296 | - | expression tag |
| His 297 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34148.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 135.1 | |
| All* | Total formula weight | 34283.3 |
