7BKO

Crystal structure of CHK1 complex with compound 9

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Serine/threonine-protein kinase Chk1	polymer	297	34148.1	1	UniProt (O14757) Pfam (PF00069) In PDB	Homo sapiens (Human)	CHK1 checkpoint homolog,Cell cycle checkpoint kinase,Checkpoint kinase-1
2	A	1H-pyrazolo[3,4-d]pyrimidin-4-amine	non-polymer		135.1	1	Chemie (TVW)
3		water	water		18.0	212	Chemie (HOH)

Sequence modifications

A: 1 - 289 (UniProt: O14757)

PDB	External Database	Details
His 290	-	expression tag
His 291	-	expression tag
His 292	-	expression tag
His 293	-	expression tag
His 294	-	expression tag
His 295	-	expression tag
His 296	-	expression tag
His 297	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	34148.1
Non-Polymers*	Number of molecules	1
	Total formula weight	135.1
All*	Total formula weight	34283.3

*Water molecules are not included.