7BH9

SARS-CoV-2 RBD-62 in complex with ACE2 peptidase domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Angiotensin-converting enzyme 2	polymer	610	70486.0	1	UniProt (Q9BYF1) Pfam (PF01401)	Homo sapiens (Human)	Angiotensin-converting enzyme homolog,ACEH,Angiotensin-converting enzyme-related carboxypeptidase,ACE-related carboxypeptidase,Metalloprotease MPROT15
2	B (E)	Spike protein S1	polymer	202	23034.0	1	UniProt (P0DTC2) Pfam (PF09408)	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2)
3	C (A)	ZINC ION	non-polymer		65.4	1	Chemie (ZN)
4	D, E, F (A)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	3	Chemie (NAG)

Sequence modifications

A: 19 - 615 (UniProt: Q9BYF1)

PDB	External Database	Details
Gly 17	-	expression tag
Ser 18	-	expression tag
Gly 616	-	expression tag
Gly 617	-	expression tag
Ser 618	-	expression tag
Gly 619	-	expression tag
Thr 620	-	expression tag
His 621	-	expression tag
His 622	-	expression tag
His 623	-	expression tag
His 624	-	expression tag
His 625	-	expression tag
His 626	-	expression tag

E: 333 - 528 (UniProt: P0DTC2)

PDB	External Database	Details
Phe 358	Ile 358	engineered mutation
Lys 445	Val 445	engineered mutation
Lys 460	Asn 460	engineered mutation
Thr 468	Ile 468	engineered mutation
Met 470	Thr 470	engineered mutation
Asn 477	Ser 477	engineered mutation
Lys 484	Glu 484	engineered mutation
Arg 498	Gln 498	engineered mutation
Tyr 501	Asn 501	engineered mutation
His 529	-	expression tag
His 530	-	expression tag
His 531	-	expression tag
His 532	-	expression tag
His 533	-	expression tag
His 534	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	93520.0
Non-Polymers*	Number of molecules	4
	Total formula weight	729.0
All*	Total formula weight	94249.0

*Water molecules are not included.