7BGG

Crystal structure of the heterocyclic toxin methyltransferase from Mycobacterium tuberculosis

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	heterocyclic toxin methyltransferase (Rv0560c)	polymer	245	26420.5	1	UniProt (P9WKL5) Pfam (PF13649)	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
2	B (A)	S-ADENOSYL-L-HOMOCYSTEINE	non-polymer		384.4	1	Chemie (SAH)
3	C, D (A)	SODIUM ION	non-polymer		23.0	2	Chemie (NA)
4	E (A)	water	water		18.0	375	Chemie (HOH)

Sequence modifications

A: 18 - 241 (UniProt: P9WKL5)

PDB	External Database	Details
Met -20	-	initiating methionine
Gly -19	-	expression tag
Ser -18	-	expression tag
Ser -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
Glu -8	-	expression tag
Asn -7	-	expression tag
Leu -6	-	expression tag
Tyr -5	-	expression tag
Phe -4	-	expression tag
Gln -3	-	expression tag
Ser -2	-	expression tag
Ala -1	-	expression tag
Gly 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	26420.5
Non-Polymers*	Number of molecules	3
	Total formula weight	430.4
All*	Total formula weight	26850.9

*Water molecules are not included.