7B7Z
DeAMPylation complex of monomeric FICD and AMPylated BiP (state 1)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (B) | Endoplasmic reticulum chaperone BiP | polymer | 523 | 57543.0 | 1 | UniProt (G3I8R9) Pfam (PF00012) | Cricetulus griseus (Chinese hamster) | 78 kDa glucose-regulated protein,GRP-78,Binding-immunoglobulin protein,BiP,Heat shock protein 70 family protein 5,HSP70 family protein 5,Heat shock protein family A member 5,Immunoglobulin heavy chain-binding protein |
| 2 | B (A) | Protein adenylyltransferase FICD | polymer | 343 | 39384.0 | 1 | UniProt (Q9BVA6) Pfam (PF02661) | Homo sapiens (Human) | AMPylator FICD,De-AMPylase FICD,FIC domain-containing protein,Huntingtin yeast partner E,Huntingtin-interacting protein 13,HIP-13,Huntingtin-interacting protein E |
| 3 | C (B) | ADENOSINE MONOPHOSPHATE | non-polymer | 347.2 | 1 | Chemie (AMP) | |||
| 4 | D (B) | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 1 | Chemie (MES) | |||
| 5 | E (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 6 | F, G (B, A) | water | water | 18.0 | 960 | Chemie (HOH) |
Sequence modifications
B: 28 - 549 (UniProt: G3I8R9)
A: 104 - 445 (UniProt: Q9BVA6)
| PDB | External Database | Details |
|---|---|---|
| Ser 27 | - | expression tag |
| Ala 229 | Thr 229 | engineered mutation |
| Phe 461 | Val 461 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Ser 103 | - | expression tag |
| Asp 258 | Leu 258 | engineered mutation |
| Ala 363 | His 363 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 96927.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 566.8 | |
| All* | Total formula weight | 97493.8 |
