7B6F

GSK3-beta in complex with compound (S)-5c

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Glycogen synthase kinase-3 beta	polymer	365	41689.8	1	UniProt (P49841) Pfam (PF00069) In PDB	Homo sapiens (Human)	GSK-3 beta,Serine/threonine-protein kinase GSK3B
2	A	3-[(3~{S})-3-[(7-chloranyl-9~{H}-pyrimido[4,5-b]indol-4-yl)-methyl-amino]piperidin-1-yl]propanenitrile	non-polymer		368.9	1	Chemie (SZW)
3	A	1,2-ETHANEDIOL	non-polymer		62.1	2	Chemie (EDO)
4	A	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
5		water	water		18.0	185	Chemie (HOH)

Sequence modifications

A: 26 - 383 (UniProt: P49841)

PDB	External Database	Details
Ala 384	-	expression tag
His 385	-	expression tag
His 386	-	expression tag
His 387	-	expression tag
His 388	-	expression tag
His 389	-	expression tag
His 390	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	41689.8
Non-Polymers*	Number of molecules	5
	Total formula weight	685.1
All*	Total formula weight	42374.9

*Water molecules are not included.