7B5K
E. coli 70S containing suppressor tRNA in the A-site stabilized by a Negamycin analogue and P-site tRNA-nascent chain.
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 23S rRNA | polymer | 2897 | 939607.3 | 1 | Escherichia coli K-12 | ||
| 2 | B (B) | 5S rRNA | polymer | 120 | 38790.1 | 1 | GenBank (CP035706.1) | Escherichia coli K-12 | |
| 3 | C (C) | 50S ribosomal protein L2 | polymer | 271 | 29663.2 | 1 | UniProt (P60422) Pfam (PF00181) Pfam (PF03947) | Escherichia coli K-12 | Large ribosomal subunit protein uL2 |
| 4 | D (D) | 50S ribosomal protein L3 | polymer | 209 | 22291.6 | 1 | UniProt (P60438) Pfam (PF00297) | Escherichia coli K-12 | Large ribosomal subunit protein uL3 |
| 5 | E (E) | 50S ribosomal protein L4 | polymer | 201 | 22121.6 | 1 | UniProt (P60723) Pfam (PF00573) | Escherichia coli K-12 | ribosomal protein uL4 |
| 6 | F (F) | 50S ribosomal protein L5 | polymer | 177 | 20073.2 | 1 | UniProt (P62399) Pfam (PF00281) Pfam (PF00673) | Escherichia coli K-12 | Large ribosomal subunit protein uL5 |
| 7 | G (G) | 50S ribosomal protein L6 | polymer | 176 | 18801.6 | 1 | UniProt (P0AG55) Pfam (PF00347) | Escherichia coli K-12 | Large ribosomal subunit protein uL6 |
| 8 | H (H) | 50S ribosomal protein L9 | polymer | 149 | 15789.0 | 1 | UniProt (P0A7R1) Pfam (PF01281) Pfam (PF03948) | Escherichia coli K-12 | ribosomal protein bL9 |
| 9 | I (J) | 50S ribosomal protein L13 | polymer | 142 | 16050.6 | 1 | UniProt (P0AA10) Pfam (PF00572) | Escherichia coli K-12 | ribosomal protein uL13 |
| 10 | J (K) | 50S ribosomal protein L14 | polymer | 123 | 13565.1 | 1 | UniProt (P0ADY3) Pfam (PF00238) | Escherichia coli K-12 | ribosomal protein uL14 |
| 11 | K (L) | 50S ribosomal protein L15 | polymer | 144 | 15008.5 | 1 | UniProt (P02413) Pfam (PF00828) | Escherichia coli K-12 | ribosomal protein uL15 |
| 12 | L (M) | 50S ribosomal protein L16 | polymer | 136 | 15327.3 | 1 | UniProt (P0ADY7) Pfam (PF00252) | Escherichia coli K-12 | Large ribosomal subunit protein uL16 |
| 13 | M (N) | 50S ribosomal protein L17 | polymer | 118 | 13505.7 | 1 | UniProt (P0AG44) Pfam (PF01196) | Escherichia coli K-12 | Large ribosomal subunit protein bL17 |
| 14 | N (O) | 50S ribosomal protein L18 | polymer | 117 | 12794.7 | 1 | UniProt (P0C018) Pfam (PF00861) | Escherichia coli K-12 | ribosomal protein uL18 |
| 15 | O (P) | 50S ribosomal protein L19 | polymer | 114 | 13028.1 | 1 | UniProt (P0A7K6) Pfam (PF01245) | Escherichia coli K-12 | Large ribosomal subunit protein bL19 |
| 16 | P (Q) | 50S ribosomal protein L20 | polymer | 117 | 13396.8 | 1 | UniProt (P0A7L3) Pfam (PF00453) | Escherichia coli K-12 | Large ribosomal subunit protein bL20 |
| 17 | Q (R) | 50S ribosomal protein L21 | polymer | 103 | 11586.4 | 1 | UniProt (P0AG48) Pfam (PF00829) | Escherichia coli K-12 | ribosomal protein bL21 |
| 18 | R (S) | 50S ribosomal protein L22 | polymer | 110 | 12253.4 | 1 | UniProt (P61175) Pfam (PF00237) | Escherichia coli K-12 | ribosomal protein uL22 |
| 19 | S (T) | 50S ribosomal protein L23 | polymer | 93 | 10546.5 | 1 | UniProt (P0ADZ0) Pfam (PF00276) | Escherichia coli K-12 | Large ribosomal subunit protein uL23 |
| 20 | T (U) | 50S ribosomal protein L24 | polymer | 102 | 11078.9 | 1 | UniProt (P60624) Pfam (PF00467) Pfam (PF17136) | Escherichia coli K-12 | Large ribosomal subunit protein uL24 |
| 21 | U (V) | 50S ribosomal protein L25 | polymer | 94 | 10713.5 | 1 | UniProt (P68919) Pfam (PF01386) | Escherichia coli K-12 | ribosomal protein bL25 |
| 22 | V (W) | 50S ribosomal protein L27 | polymer | 76 | 8275.5 | 1 | UniProt (P0A7L8) Pfam (PF01016) | Escherichia coli K-12 | Large ribosomal subunit protein bL27 |
| 23 | W (X) | 50S ribosomal protein L28 | polymer | 77 | 8896.4 | 1 | UniProt (P0A7M2) Pfam (PF00830) | Escherichia coli K-12 | Large ribosomal subunit protein bL28 |
| 24 | X (Y) | 50S ribosomal protein L29 | polymer | 62 | 7155.3 | 1 | UniProt (P0A7M6) Pfam (PF00831) | Escherichia coli K-12 | Large ribosomal subunit protein uL29 |
| 25 | Y (Z) | 50S ribosomal protein L30 | polymer | 58 | 6423.6 | 1 | UniProt (P0AG51) Pfam (PF00327) | Escherichia coli K-12 | Large ribosomal subunit protein uL30 |
| 26 | Z (0) | 50S ribosomal protein L32 | polymer | 56 | 6332.2 | 1 | UniProt (P0A7N4) Pfam (PF01783) | Escherichia coli K-12 | Large ribosomal subunit protein bL32 |
| 27 | AA (1) | 50S ribosomal protein L33 | polymer | 51 | 5928.0 | 1 | UniProt (P0A7N9) Pfam (PF00471) | Escherichia coli K-12 | Large ribosomal subunit protein bL33 |
| 28 | BA (2) | 50S ribosomal protein L34 | polymer | 46 | 5397.5 | 1 | UniProt (P0A7P5) Pfam (PF00468) | Escherichia coli K-12 | ribosomal protein bL34 |
| 29 | CA (3) | 50S ribosomal protein L35 | polymer | 64 | 7181.8 | 1 | UniProt (P0A7Q1) Pfam (PF01632) | Escherichia coli K-12 | Large ribosomal subunit protein bL35,Ribosomal protein A |
| 30 | DA (4) | 50S ribosomal protein L36 | polymer | 38 | 4377.4 | 1 | UniProt (P0A7Q6) Pfam (PF00444) | Escherichia coli K-12 | Ribosomal protein B, ribosomal protein bL36 |
| 31 | EA (5) | 50S ribosomal protein L31 | polymer | 66 | 7516.7 | 1 | UniProt (P0A7M9) Pfam (PF01197) | Escherichia coli K-12 | Large ribosomal subunit protein bL31-A |
| 32 | FA (a) | 16S rRNA | polymer | 1533 | 497074.8 | 1 | Escherichia coli K-12 | ||
| 33 | GA (b) | 30S ribosomal protein S2 | polymer | 224 | 24971.8 | 1 | UniProt (A0A3K3SDJ5) | Escherichia coli K-12 | |
| 34 | HA (c) | 30S ribosomal protein S3 | polymer | 206 | 23078.8 | 1 | UniProt (P0A7V3) Pfam (PF07650) Pfam (PF00189) | Escherichia coli K-12 | Small ribosomal subunit protein uS3 |
| 35 | IA (d) | 30S ribosomal protein S4 | polymer | 205 | 23383.0 | 1 | UniProt (P0A7V8) Pfam (PF00163) Pfam (PF01479) | Escherichia coli K-12 | Small ribosomal subunit protein uS4 |
| 36 | JA (e) | 30S ribosomal protein S5 | polymer | 155 | 16361.9 | 1 | UniProt (P0A7W1) Pfam (PF00333) Pfam (PF03719) | Escherichia coli K-12 | Small ribosomal subunit protein uS5 |
| 37 | KA (f) | 30S ribosomal protein S6 | polymer | 106 | 12326.3 | 1 | UniProt (P02358) Pfam (PF01250) | Escherichia coli K-12 | Small ribosomal subunit protein bS6 |
| 38 | LA (g) | 30S ribosomal protein S7 | polymer | 151 | 16861.5 | 1 | UniProt (P02359) Pfam (PF00177) | Escherichia coli K-12 | Small ribosomal subunit protein uS7 |
| 39 | MA (h) | 30S ribosomal protein S8 | polymer | 129 | 14015.4 | 1 | UniProt (P0A7W7) Pfam (PF00410) | Escherichia coli K-12 | Small ribosomal subunit protein uS8 |
| 40 | NA (i) | 30S ribosomal protein S9 | polymer | 127 | 14554.9 | 1 | UniProt (P0A7X3) Pfam (PF00380) | Escherichia coli K-12 | Small ribosomal subunit protein uS9 |
| 41 | OA (j) | 30S ribosomal protein S10 | polymer | 99 | 11325.1 | 1 | UniProt (P0A7R5) Pfam (PF00338) | Escherichia coli K-12 | Small ribosomal subunit protein uS10,Transcription termination/antitermination protein NusE |
| 42 | PA (k) | 30S ribosomal protein S11 | polymer | 117 | 12487.2 | 1 | UniProt (P0A7R9) Pfam (PF00411) | Escherichia coli K-12 | Small ribosomal subunit protein uS11 |
| 43 | QA (l) | 30S ribosomal protein S12 | polymer | 123 | 13683.1 | 1 | UniProt (P0A7S3) Pfam (PF00164) | Escherichia coli K-12 | Small ribosomal subunit protein uS12 |
| 44 | RA (m) | 30S ribosomal protein S13 | polymer | 114 | 12625.8 | 1 | UniProt (P0A7S9) Pfam (PF00416) | Escherichia coli K-12 | Small ribosomal subunit protein uS13 |
| 45 | SA (n) | 30S ribosomal protein S14 | polymer | 101 | 11546.4 | 1 | UniProt (P0AG59) Pfam (PF00253) | Escherichia coli K-12 | Small ribosomal subunit protein uS14 |
| 46 | TA (o) | 30S ribosomal protein S15 | polymer | 88 | 10159.6 | 1 | UniProt (P0ADZ4) Pfam (PF00312) | Escherichia coli K-12 | Small ribosomal subunit protein uS15 |
| 47 | UA (p) | 30S ribosomal protein S16 | polymer | 82 | 9207.6 | 1 | UniProt (P0A7T3) Pfam (PF00886) | Escherichia coli K-12 | Small ribosomal subunit protein bS16 |
| 48 | VA (q) | 30S ribosomal protein S17 | polymer | 80 | 9263.9 | 1 | UniProt (P0AG63) Pfam (PF00366) | Escherichia coli K-12 | Small ribosomal subunit protein uS17 |
| 49 | WA (r) | 30S ribosomal protein S18 | polymer | 55 | 6466.5 | 1 | UniProt (P0A7T7) Pfam (PF01084) | Escherichia coli K-12 | Small ribosomal subunit protein bS18 |
| 50 | XA (s) | 30S ribosomal protein S19 | polymer | 82 | 9323.9 | 1 | UniProt (P0A7U3) Pfam (PF00203) | Escherichia coli K-12 | Small ribosomal subunit protein uS19 |
| 51 | YA (t) | 30S ribosomal protein S20 | polymer | 86 | 9577.3 | 1 | UniProt (P0A7U7) Pfam (PF01649) | Escherichia coli K-12 | Small ribosomal subunit protein bS20 |
| 52 | ZA (u) | 30S ribosomal protein S21 | polymer | 56 | 6629.7 | 1 | UniProt (P68679) Pfam (PF01165) | Escherichia coli K-12 | Small ribosomal subunit protein bS21 |
| 53 | AB (v) | ermC Nacent chain | polymer | 8 | 895.1 | 1 | Escherichia coli K-12 | ||
| 54 | BB (x) | P-site Isoleucine tRNA (77-MER) | polymer | 77 | 24839.8 | 1 | Escherichia coli K-12 | ||
| 55 | CB (z) | atRNA synthetic Stop tRNA (76-MER) | polymer | 76 | 24632.7 | 1 | Escherichia coli K-12 | ||
| 56 | DB (9) | E-site val tRNA (76-MER) | polymer | 76 | 24444.5 | 1 | Escherichia coli K-12 | ||
| 57 | EB (6) | mRNA | polymer | 11 | 3491.1 | 1 | Escherichia coli K-12 | ||
| 58 | AC, AD, AE, AF, AG... (A, a, m, B, C...) | MAGNESIUM ION | non-polymer | 24.3 | 359 | Chemie (MG) | |||
| 59 | HK (A) | ERYTHROMYCIN A | non-polymer | 733.9 | 1 | Chemie (ERY) | |||
| 60 | YO, ZO (a) | 2-[[[(3~{R},5~{R})-3-azanyl-6-(3-azanylpropylamino)-5-oxidanyl-hexanoyl]amino]-methyl-amino]ethanoic acid | non-polymer | 305.4 | 2 | Chemie (SY5) | |||
| 61 | DP, EP, FP, GP, HP... (A, C, D, L, N...) | water | water | 18.0 | 854 | Chemie (HOH) |
Sequence modifications
n: 1 - 101 (UniProt: P0AG59)
| PDB | External Database | Details |
|---|---|---|
| Ala 35 | - | insertion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 57 |
| Total formula weight | 2186704.7 | |
| Non-Polymers* | Number of molecules | 362 |
| Total formula weight | 10070.2 | |
| All* | Total formula weight | 2196774.9 |
