7B55
Crystal structure of CaMKII-actinin complex bound to MES
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | B | Calcium/calmodulin-dependent protein kinase type II subunit alpha | polymer | 317 | 35903.4 | 1 | UniProt (P11798) Pfam (PF00069) In PDB | Mus musculus (Mouse) | CaMK-II subunit alpha |
2 | A | Alpha-actinin-2 | polymer | 73 | 7903.8 | 1 | UniProt (P35609) Pfam (PF08726) In PDB | Homo sapiens (Human) | Alpha-actinin skeletal muscle isoform 2,F-actin cross-linking protein |
3 | B | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 2 | Chemie (MES) | |||
4 | water | water | 18.0 | 383 | Chemie (HOH) |
Sequence modifications
B: 1 - 315 (UniProt: P11798)
A: 825 - 894 (UniProt: P35609)
PDB | External Database | Details |
---|---|---|
Ser -1 | - | expression tag |
Met 0 | - | expression tag |
Ala 305 | Thr 305 | engineered mutation |
Ala 306 | Thr 306 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Ser 822 | - | expression tag |
Asn 823 | - | expression tag |
Ala 824 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 43807.2 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 390.5 | |
All* | Total formula weight | 44197.7 |