7B55
Crystal structure of CaMKII-actinin complex bound to MES
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (B) | Calcium/calmodulin-dependent protein kinase type II subunit alpha | polymer | 317 | 35903.4 | 1 | UniProt (P11798) Pfam (PF00069) | Mus musculus (Mouse) | CaMK-II subunit alpha |
| 2 | B (A) | Alpha-actinin-2 | polymer | 73 | 7903.8 | 1 | UniProt (P35609) Pfam (PF08726) | Homo sapiens (Human) | Alpha-actinin skeletal muscle isoform 2,F-actin cross-linking protein |
| 3 | C, D (B) | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 2 | Chemie (MES) | |||
| 4 | E, F (B, A) | water | water | 18.0 | 383 | Chemie (HOH) |
Sequence modifications
B: 1 - 315 (UniProt: P11798)
A: 825 - 894 (UniProt: P35609)
| PDB | External Database | Details |
|---|---|---|
| Ser -1 | - | expression tag |
| Met 0 | - | expression tag |
| Ala 305 | Thr 305 | engineered mutation |
| Ala 306 | Thr 306 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Ser 822 | - | expression tag |
| Asn 823 | - | expression tag |
| Ala 824 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 43807.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 390.5 | |
| All* | Total formula weight | 44197.7 |
