7B3K
Dynamic complex between all-D-enantiomeric peptide D3 with L723P mutant of amyloid precursor protein (APP) 672-726 fragment (amyloid beta 1-55)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Isoform L-APP677 of Amyloid-beta precursor protein | polymer | 55 | 5975.0 | 1 | UniProt (P05067) Pfam (PF03494) In PDB | Homo sapiens (Human) | APP,ABPP,APPI,Alzheimer disease amyloid protein,Amyloid precursor protein,Amyloid-beta A4 protein,Cerebral vascular amyloid peptide,CVAP,PreA4,Protease nexin-II,PN-II |
| 2 | B | D3 all D-enantimeric peptide | polymer | 12 | 1606.9 | 1 | synthetic construct |
Sequence modifications
A: 1 - 55 (UniProt: P05067)
| PDB | External Database | Details |
|---|---|---|
| Pro 52 | Leu 630 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 7581.9 | |
| All* | Total formula weight | 7581.9 |
